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02-10-2009, 04:33 PM
Evacet is for intravenous (IV) use only. If Evacet accidentally leaks into surrounding tissue, the skin or muscle may be severely damaged. Notify your doctor immediately if redness, pain, or swelling at or around the injection site occur. Evacet may cause heart problems (eg, heart failure) or bone marrow suppression. Notify your doctor immediately if you develop an irregular heartbeat, trouble breathing, swelling of the hands or feet, easy bruising or bleeding, a dry cough, or signs of an infection (eg, fever, unusual tiredness, persistent sore throat). Heart problems may occur during therapy or sometimes months to years after receiving Evacet. The risk of developing heart problems varies depending on your dose and condition. The risk may be increased if you have a history of radiation therapy or if you are using cyclophosphamide. Tell your doctor if you have liver problems because your dose will have to be decreased. Your doctor will closely monitor you while you are using Evacet.
Doxorubicin liposomal should only be administered under the supervision of a qualified health care provider experienced in the use of cancer chemotherapeutic agents.
Some medical conditions may interact with Evacet. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have kidney, liver or heart disease
if you have liver problems
if you have had radiation therapy
if you have poor bone marrow function
if you have previously received treatment with other anticancer medicines (eg, daunorubicin, idarubicin, another anthracycline or anthracene)
Some MEDICINES MAY INTERACT with Evacet. Tell your health care provider if you are taking any other medicines, especially any of the following:
Barbiturates (eg, phenobarbital) or streptozocin because they may decrease Evacet's effectiveness
Calcium channel blockers (eg, verapamil), cyclophosphamide, cyclosporine, or paclitaxel because the risk of side effects, such as heart problems, may be increased
Anticoagulants (eg, warfarin) or trastuzumab because their actions and the risk of their side effects may be increased by Evacet
Carbamazepine, digoxin, hydantoins (eg, phenytoin), live vaccines, or valproic acid because their effectiveness may be decreased by Evacet
This may not be a complete list of all interactions that may occur. Ask your health care provider if Evacet may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Doxorubicin liposomal is in the FDA pregnancy category D. This means that doxorubicin liposomal is known to be harmful to an unborn baby. Do not use doxorubicin liposomal without first talking to your doctor if you are pregnant. Discuss with your doctor the appropriate use of birth control during, and for several months following, treatment with doxorubicin liposomal if necessary. Because of the potential for serious side effects in a nursing infant, breast-feeding should be avoided during treatment with doxorubicin liposomal.
Doxorubicin liposomal should only be administered under the supervision of a qualified health care provider experienced in the use of cancer chemotherapeutic agents.
Some medical conditions may interact with Evacet. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you have kidney, liver or heart disease
if you have liver problems
if you have had radiation therapy
if you have poor bone marrow function
if you have previously received treatment with other anticancer medicines (eg, daunorubicin, idarubicin, another anthracycline or anthracene)
Some MEDICINES MAY INTERACT with Evacet. Tell your health care provider if you are taking any other medicines, especially any of the following:
Barbiturates (eg, phenobarbital) or streptozocin because they may decrease Evacet's effectiveness
Calcium channel blockers (eg, verapamil), cyclophosphamide, cyclosporine, or paclitaxel because the risk of side effects, such as heart problems, may be increased
Anticoagulants (eg, warfarin) or trastuzumab because their actions and the risk of their side effects may be increased by Evacet
Carbamazepine, digoxin, hydantoins (eg, phenytoin), live vaccines, or valproic acid because their effectiveness may be decreased by Evacet
This may not be a complete list of all interactions that may occur. Ask your health care provider if Evacet may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Doxorubicin liposomal is in the FDA pregnancy category D. This means that doxorubicin liposomal is known to be harmful to an unborn baby. Do not use doxorubicin liposomal without first talking to your doctor if you are pregnant. Discuss with your doctor the appropriate use of birth control during, and for several months following, treatment with doxorubicin liposomal if necessary. Because of the potential for serious side effects in a nursing infant, breast-feeding should be avoided during treatment with doxorubicin liposomal.