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Adrenocortical Carcinoma
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Orphagen Pharmaceuticals Awarded Federal Grant for Adrenocortical and Prostate Cancer

Posted 08-13-2010 at 02:31 PM by admin
2010-08-10, Source: Orphagen Pharmaceuticals

Orphagen Pharmaceuticals announced today that the National Cancer Institute (NCI) has awarded a Phase I SBIR grant to the Company for development of a new class of small molecule drugs for the treatment of adrenocortical and prostate cancer. The objective of the studies is to demonstrate that the Company's proprietary small molecules are effective at physiological targets that will enhance therapy for these two devastating diseases. Adrenocortical...
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Decitabine had antitumoral effect on adrenocortical carcinoma

Posted 05-04-2010 at 07:28 PM by admin
HemOnc today
Posted May 3, 2010

The DNA promoter methylation inhibitor decitabine exhibited some antitumor properties in tests of adrenocortical carcinoma cells. The drug’s activity in recovering gene expression suggests that gene silencing on chromosome 11q13 may play a role in the rare malignancy’s origin.

“Decitabine reverses the classic epigenetic alteration, DNA promoter methylation,” researchers wrote. “It acts by removing inhibitory methyl groups from the...
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Clipless & sutureless laparoscopic adrenalec. carried out w/ LigaSure dev. in 32 pat.

Posted 04-28-2010 at 05:43 PM by admin
Clipless and sutureless laparoscopic adrenalectomy carried out with the LigaSure device in 32 patients - Abstract

Uro Today
Wednesday, 28 April 2010

Department of General Surgery, Fatih University School of Medicine, Ankara, Turkey.

litotemexi@yahoo.com.tr

Laparoscopic adrenalectomy has become the standard procedure for treating patents with adrenal masses. The purpose of this study was to evaluate the use of the LigaSure vessel closure...
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Revolutionary Drug Could Be New Hope for Adrenal Cancer Patients

Posted 09-29-2009 at 04:24 PM by admin
OSI-906 in clinical trial for adrenocortical carcinoma

SCOTTSDALE, Ariz., Sept. 22 /PRNewswire-USNewswire/ -- TGen Clinical Research Services at Scottsdale Healthcare today announced the start of a clinical trial for a drug designed to combat adrenocortical carcinoma (ACC), a rare but deadly cancer that attacks the adrenal glands.

TCRS is a strategic alliance between the Translational Genomics Research Institute (TGen) and Scottsdale Healthcare.

Other than...
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G-E Profiling Predicts Tumor Recur. & Surv. for Patients With Adrenocortical Tumors

Posted 05-01-2009 at 02:25 PM by admin
Gene-Expression Profiling Predicts Tumour Recurrence and Survival for Patients With Adrenocortical Tumours: Presented at ECE

By Chris Berrie

ISTANBUL, Turkey -- April 29, 2009 -- Routine analysis for the expression of 2 specific 2-gene combinations in patients with adrenocortical tumours can reliably predict the risk of tumour recurrence independent of pathology and can also predict the risk of death independent of tumour stage, according to research presented here at the...
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