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Azacitidine
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Appeal ruling forces NICE rethink on Vidaza for MDS

Posted 07-27-2010 at 05:57 PM by admin
PharmaTimes
By Selina McKee
26 July 2010

Patients in the UK with myelodysplastic syndromes will be celebrating news that the National Institute for Health and Clinical Excellence has been ordered to reassess Celgene’s Vidaza for the National Health Service.

An Appeal Board has agreed with certain objections voiced in appeals by Celgene and a whole host of other bodies - including Royal Colleges and support group MDS UK - against a ruling by the cost watchdog...
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Small trial hints at a new direction for epigenetic therapy

Posted 07-08-2010 at 02:04 PM by admin
Oncology NEWS Today Blog.
By Lois Wingerson | July 7, 2010

Epigenetic cancer therapies–drugs that reverse abnormalities in how DNA is packaged within the nucleus–clearly work for a while against some tumors, and some of these have been approved by FDA. Although they represent an important new class of therapies in hematological malignancies such as myelodysplasia or acute myeloid leukemia, their mechanism of action remains unknown. A number of possible mechanisms of action have...
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Cancer experts from across Europe call for expensive cancer drug on NHS

Posted 05-28-2010 at 02:43 PM by admin
By Kate Devlin, Medical Correspondent
Published: 7:30AM BST 28 May 2010

Cancer experts from more than 30 hospitals across Europe have joined a campaign to get an expensive life-extending drug on the NHS.

The doctors have called on the Government’s drugs rationing body to give terminally ill cancer patients the drug azacitidine.

The medication treats rare cancers of the blood and bone marrow.

But the drug, also known as Vidaza, has been...
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Vidaza to Keep Propri. Clin. Gold Stand. Status for Myelodysplastic Syndromes Treat.

Posted 04-28-2010 at 04:24 PM by admin
Celgene's Vidaza to Retain Proprietary Clinical Gold Standard Status for the Treatment of Myelodysplastic Syndromes

TradingMarkets.com
Posted on: Wed, 28 Apr 2010 00:59:22 EDT

Apr 28, 2010 (Close-Up Media via COMTEX)

Decision Resources, a research and advisory firms for pharmaceutical and healthcare issues, finds that Celgene's Vidaza (azacitidine) (seven-day dosing) will retain Decision Resources' proprietary clinical gold standard status through 2013...
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Bone Marrow Cancer Patients May Benefit From Drug Combo

Posted 03-30-2010 at 08:22 PM by admin
Small study had successful results in myelodysplastic syndrome patients

MONDAY, March 29 (HealthDay News) -- The drugs azacitidine and lenalidomide provide a highly effective combination treatment for bone marrow cancer, according to the results of a new study.

The phase 1 study, which was funded by the U.S. National Institutes of Health, included 18 higher-risk patients, median age 68, with myelodysplastic syndromes (MDS). In people with this cancer (which is similar...
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