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Bortezomib
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ARF Can Be First Sign of Multiple Myeloma

Posted 02-05-2010 at 01:50 PM by admin
Renal & Urology News
Caroline Helwick
February 05, 2010

NEW ORLEANS—Acute renal failure (ARF) induced by pathogenic light chains can be the first presenting sign of multiple myeloma, and prompt treatment of the malignancy is critical to reversing renal damage, according to a study presented by European investigators at the American Society of Hematology 51st annual meeting.

“This is an oncologic emergency and you need very active myeloma treatment to correct...
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Drug Shows Promise as New Treatment for Gut Tumor

Posted 02-01-2010 at 07:41 PM by admin
ScienceDaily (Jan. 14, 2010) — A drug that is already an approved therapy for some cancers also might be an effective secondary treatment for a rare tumor of the gastrointestinal tract, according to a team led by researchers from the University of Pittsburgh Cancer Institute (UPCI). The findings, based on experiments using cell cultures, were published in the Jan. 1 issue of Cancer Research.

Bortezomib, or Velcade, is used to treat multiple myeloma and certain lymphomas, said Anette...
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Phase 2 Study Res. of Perifosine as Sin. Agent for Treat. of Adv. Waldenstrom's Mac.

Posted 01-29-2010 at 02:07 PM by admin
Keryx Biopharmaceuticals Announces Positive Phase 2 Study Results of Perifosine as a Single Agent for the Treatment of Advanced Waldenstrom's Macroglobulinemia

Data Demonstrating a 35% Overall Response Rate with a Median Progression-Free Survival of 12.6 Months in Patients with Relapsed or Relapsed/Refractory Waldenstrom's Macroglobulinemia to be Published in the February 1, 2010 Issue of Clinical Cancer Research

NEW YORK, Jan. 29 /PRNewswire-FirstCall/ -- Keryx Biopharmaceuticals,...
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Velcade patients live longer in myeloma study

Posted 12-14-2009 at 01:33 PM by admin
Mon Dec 7, 2009 7:00pm EST

* Reduced risk of death 35 pct over standard drugs alone

* Velcade plus standard drugs 68.5 pct overall survival

* Standard melphalan/prednisone 54 pct overall survival

* Melphalan/prednisone median overall survival 43.1 months

* Median overall survival not yet reached in Velcade group

By Bill Berkrot

NEW YORK, Dec 7 (Reuters) - Patients with previously untreated multiple myeloma...
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Bortezomib,thalidomide + standard multiple myeloma treatments improve response

Posted 12-09-2009 at 03:37 PM by admin
Adding bortezomib, thalidomide to standard multiple myeloma treatments improved response in older patients

HemOnc today
Posted December 5, 2009

Pairing bortezomib with either melphalan/prednisone or thalidomide/prednisone resulted in favorable response rates among older patients with multiple myeloma, according to data presented at the 51st ASH Annual Meeting.

In addition, lowering the doses of the therapies at induction in favor of maintenance therapy...
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