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Chronic Myeloproliferative Disorders
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McGill plays important role in new global cancer-research network

Posted 04-15-2010 at 07:18 PM by admin
EurekAlert!
Source: McGill University

Public release date: 15-Apr-2010
Contact: William Raillant-Clark
william.raillant-clark@mcgill.ca
514-398-2189
McGill University

International Cancer Genome Consortium plans to sequence 25,000 cancer genomes

This press release is available in French.

A new network was announced today by the International Cancer Genome Consortium (ICGC), and Dr. Bartha Knoppers, Director of the...
Administrator
Posted in Brain and Spinal Cord Tumors, Brain Stem Glioma, Brain Tumor, Central Nervous System Atypical Teratoid/Rhabdoid Tumor, Central Nervous System Embryonal Tumors, Cerebellar Astrocytoma, Chronic Myeloproliferative Disorders, Colon Cancer, Cutaneous T-Cell Lymphoma, Ependymoma, Gastric (Stomach) Cancer, Chronic Myelogenous Leukemia, Leukemia, Hairy Cell Leukemia, Chronic Lymphocytic Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Promyelocytic Leukemia, Lip and Oral Cavity Cancer, Liver Cancer, Lung Cancer, Lymphoma, Non-Hodgkin Lymphoma, Hodgkin Lymphoma, Primary Central Nervous System Lymphoma, Medulloblastoma, Multiple Myeloma, Multiple Myeloma and Other Plasma Cell Neoplasms, Mycosis Fungoides, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases, Ovarian Cancer, Pancreatic Cancer, Pineoblastoma, Renal Cell (Kidney) Cancer, Sézary Syndrome, Supratentorial Primitive Neuroectodermal Tumors, Waldenström Macroglobulinemia
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Drug Resistance in Myeloproliferative Disorders Can be Overcome

Posted 04-17-2009 at 09:14 PM by admin
By Nancy Lapid

NEW YORK DEC 24, 2008 (Reuters Health) - A newly identified apoptosis pathway is inhibited in cancerous myeloid cells, making them resistant to treatment. However, the researchers who identified this pathway have also discovered how to override its inhibition and restore the cells' susceptibility to chemotherapy.

They describe their findings in the December 25th issue of The New England Journal of Medicine.

The investigators, led by Dr. Denis...
Administrator
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Genetic Abnormality May Increase Risk of Blood Disorders

Posted 03-17-2009 at 06:41 PM by admin
Newswise — Researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) have shown for the first time that a tendency to develop some blood disorders may be inherited. Their research, published online today in Nature Genetics, identifies a common genetic sequence abnormality that enhances the likelihood of acquiring a mutation in a gene linked to certain blood diseases.

The investigators carried out a genome-wide study to identify inherited DNA sequence changes that frequently occur...
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