By Crystal Phend, Senior Staff Writer, MedPage Today
Published: April 28, 2010
Reviewed by Dori F. Zaleznik, MD; Associate Clinical Professor of Medicine, Harvard Medical School, Boston.
Heating the area around a high-risk soft-tissue sarcoma during chemotherapy can boost antitumor efficacy and improve survival, researchers found.
Regional hyperthermia during induction was associated with a 42% reduction in risk of local progression or death compared with chemotherapy...
(Philadelphia, PA) — Src (short for sarcoma) is a family of proto-oncogenic tyrosine kinases active in many cancer tumors, including medulloblastoma, the most common malignant cancer in children. Src represents one of the most promising targets for cancer therapy.
A recent study shows that pyrazolo-[3,4-d]–pyrimidine-derivatives, designed to target Src, may...
Fri Sep 4, 2009 12:13pm EDTScienceDaily (Sep. 8, 2009) — A common weed called American mayapple may soon offer an alternative to an Asian cousin that's been harvested almost to extinction because of its anti-cancer properties. The near-extinct Asian plant, Podophyllyum emodi, produces podophyllotoxin, a compound used in manufacturing etoposide, the active ingredient in a drug used for treating lung and testicular cancer. Podophyllyum emodi is a cousin of the common mayapple weed found in the United...
AJHO: The American Journal of Hematology/Oncology
August 18, 2009
● RESEARCHERS OF THE CHILDREN'S ONCOLOGY GROUP HAVE DEVELOPED a new chemotherapy regimen known as ABVE-PC to treat patients with pediatric Hodgkin lymphoma (HL). Led by Cindy Schwartz, MD, director of pediatric hematology/ oncology at Hasbro Children's Hospital in Providence, Rhode Island, the group combined six different drugs into a dose-dense regimen that achieves rapid early response and limits...
NEW YORK AUG 19, 2008 (Reuters Health) - Women with high-risk gestational trophoblastic neoplasia, as well as those who fail initial single-agent therapy, should be referred to a specialized trophoblastic disease center to maximize the chance for cure, physicians at Northwestern University in Chicago recommend.
Gestational trophoblastic neoplasia is one of the most curable of all human tumors, Dr. John R. Lurain and colleagues note in the August issue of Obstetrics & Gynecology....
